According to the federal Centers for Disease Control and Prevention, 61 million Americans suffer from cardiovascular disease. Cardiovascular disease covers a broad range of disorders including high blood pressure, heart attack and chest pain, stroke, congestive heart failure and birth defects of the blood vessels. Every year, heart attacks and strokes cause more than 930,000 deaths in the US accounting for over 40% of all deaths making it the nation’s number one killer.
As a matter of fact, every 34 seconds an American dies of heart disease. Most of us know someone that has heart disease and most of us are interested in avoiding the health problems associated with this disease. The good news is that are tools available as well as very good information at our finger-tips that help us outline a program to help control many types of heart disease.
While cardiovascular disease kills primarily people 65 and older, the incidence of sudden death from heart disease is dramatically rising in people aged from 15 to 34 years of age.
What is Cholesterol
Cholesterol is a fatty acid component found in virtually all cell membranes. Not only does cholesterol support cellular integrity, but cholesterol also is required for the transport of phospholipids into our cells. If we didn’t have cholesterol we would fall apart. Cholesterol is what makes our cells waterproof. Without cholesterol we could not a different biochemistry on the inside and the outside of our cell.
When cholesterol levels are not adequate, the cell membrane becomes leaky and porous, a situation the body interprets as an emergency, releasing a flood of corticoid hormones that wok by sequestering cholesterol from one part of the body and transporting it to areas where it is lacking. This can become a problem when medications are used to drive cholesterol levels down too low.
Another interesting fact is that our liver makes approximately 80 percent of the cholesterol in our body. Approximately 20 percent comes from the diet. Focusing on just lowering cholesterol and fat consumption has little or no effect on serum cholesterol levels. A diet high in carbohydrates especially refined carbs and starches and other fast acting starches and hydrogenated fats is more likely to cause an increase in total cholesterol than cholesterol from food.
Our body is very smart, especially when it comes to maintaining balance. For example, our liver will produce cholesterol if needed and will slow down production if cholesterol is not needed. We were given this as a fed back mechanism to continually strive to maintain balance in our body chemistry.
The greatest effect on lowering total cholesterol levels are made by addressing other factors such as excessive carbohydrate consumption, sedentary lifestyle, smoking, endocrine dysfunction and liver congestion.
Medical Approach
After the Cholesterol Consensus Conference in 1984 anyone with a cholesterol level of 200 or more was automatically given a prescription. If you have ever had cardiovascular disease in the past you will almost automatically be put on a statin.
Cholesterol lowering medications such as HMG-CoA reductase inhibitors Lipitor, Mevacor, Pravachol, Lescol and Zorcor are commonly prescribed. Statin drugs work by inhibiting an enzyme called HMG-CoA reductase. This can be the beginning of numerous other problems or symptoms because statin drugs inhibit not only the production of cholesterol, but the whole family of intermediate substances, many if not all which have important biochemical functions in their own right.
If you follow any news stories recently, one can see many of these medications are being looked at very closely because of the potential adverse side effects. Another common complaint from people on statins is chronic muscle pain. Some information that has been published in regard to chronic muscle pain looks at a couple things.
First, the statins can interfere with liver function. If our liver does not detoxify or work properly, it can become sluggish and cause any number of health problems or symptoms. Secondly, for the statins to be metabolized in our body, we need to have available the nutrient called CoQ10. The interesting point about CoQ10 is that it is needed for energy production and has been shown to be deficient in many individuals, especially those that are taking the statin medications.
Recent research from Germany is suggesting that Lipitor is no more effective than any other cholesterol lowering drug on the market. The manufacturer claims it is the best available. This is what the manufacturers want you to think so you can take it the rest of your life and spending thousands upon thousands of dollars on this drug.
In addition, recent information is suggesting that regularly taking statin drug may prevent strokes. Again, there is much research showing that certain nutrients and dietary intervention can be very effective in reducing the event of stroke. Lipitor is on track this year (2006) to make an estimated 13 billion dollars by year end.
Another problem is that the New England Journal of Medicine recently published a report finding that Lipitor more than doubled the risk for a deadly stroke if you’re a severe diabetic. Plus a study funded by Pfizer compared the effect of a 20mg dose of Lipitor verses placebo on more than 1200 type II diabetics who were ill over a four year period.
The results were as follows: Taking Lipitor made absolutely no difference in the participants combined risk of heart attacks, strokes and death. Even worse, more than twice as many patients who took Lipitor suffered fatal strokes (27) than the placebo group (13).
Liver function is generally monitored as enzymes may be elevated in individuals that do not do well with the statin drugs. This is also important to remember if one wants to improve liver function or even protect it from the side effects that may arise from the use of certain medications. There is a great amount of literature to support the idea that we should cleanse the live in conjunction with other dietary changes to maximize the lowering of total cholesterol.
New guidelines published by the American College of Physicians call for using statins by all people with diabetes older than 55 years old and for younger diabetic patients who have any other risk factor for heart disease such as high blood pressure or a history of smoking. The sales of statins have been so impressive that it is being considered to be used in many other health conditions including:
- Cancer
- Multiple sclerosis
- Osteoporosis
- Macular Degeneration
- Arthritis
- Mental disorders such as memory and learning problems., Alzheimer’s and dementia.
Cost of statin drugs
With all the information put forth on the lowering of cholesterol, the statin medications are enjoying a spike in sales. Unfortunately, the statin drugs while very effective also have side effects that many people don’t want to experience. The cost of some statin medications run up to $300 per month.
First Step
Determining Your Cardiovascular Health
The first step is to accurately measure your current condition. We get disease if cholesterol is too high or too low. Below 180 there is an increased risk of hemorrhagic stroke, depression, and suicide. Above 240 there is an increased risk of cardiovascular disease and ischemic stroke. Half of all heart attack patients have normal cholesterol levels.
Recently, the upper limit of total cholesterol went from 220 down to 200 and is being considered to go even lower. But is this the absolute answer to risk for heart disease? Probably not. Nevertheless the side effects of the statin drugs may be significant. There is supportive literature to look at optimal values of lab rather than just looking at normal ranges of lab for everyone.
Cholesterol levels fall into several different ranges. Conventional Laboratory Range, Optimal Range and Alarm Range.
Conventional Lab Range: 130-200 mg/dL(Standard US Units) 3.36-5.2 mmol/L(Standard International Units)
Optimal Range: 150-220 mg/dL(Standard US Units) 3.9-5.69 mmol/L(Standard International Units)
Alarm Range: <50 or > 400 mg/dL(Standard US Units) <1.29 or >10.34 mmol/L(Standard International Units)
Too low of a cholesterol level can also suggest a concern for other health problems.
In some of the statins, CoQ10 is needed to metabolize the medications, ultimately leaving a deficiency. This deficiency is correlated with most types of cardiovascular disease. In others, the statins interfere with cholesterol metabolism in the liver causing liver damage in some this is exactly why many physicians are recommending including CoQ10 to their patients taking statin drugs.
Many Medical Laboratories now subdivide total cholesterol measurement into several components, including LDL (bad) cholesterol which is directly linked to heart disease, actually one can request a highly sensitive large particle LDL blood test that will actually look at the stickiness of the blood to determine actual risk factors for clotting. Standard tests also look at the HDL (good) cholesterol that is protective. The relative amount of LDL to HDL is more important than total cholesterol. An example is that is possible for an individual to have a very high HDL to be at low risk for heart disease even with the total cholesterol above 200.
Many studies are looking at measuring inflammation in the blood and tissues rather than cholesterol as a way to determine risk factors for heart disease. The name of this test is called a C-reactive protein Test (CRP Cardio).
One must keep in mind that optimal health is about balance. Too low of cholesterol can have a detrimental effect on health as well. Consider the fact that your body produces cholesterol primarily in the liver and other tissues, whether you eat food or not. Cholesterol is the backbone
Second Step
Control Inflammation
More and more recent research is proving that inflammation plays a role in almost every health condition, especially heart disease. The New England Journal of Medicine recently published 3 articles showing the connection between inflammation and determining heart disease. There are several test one can do to determine the amount of inflammation in the bodies tissues.
One test is called Fibrinogen. High fibrinogen levels can induce a heart attack via a couple mechanisms including platelet aggregation, hyper-coagulation and excessive blood thickening. High levels of fibrinogen doubled the risk to die from a heart attack.
High fibrinogen has been shown to respond nicely to several lifestyle changes and dietary supplements.
Stress reduction, regular exercise can be helpful. Dietary supplements include but are not limited to the following: Bolouke, proteolytic enzymes, vitamin C, Green Tea, ginkgo, garlic and vitamin E. It is also recommended to look at DHEA and vitamin K levels.
One very helpful test is the C-reactive protein test that measures the inflammation in your blood and tissues. One drawback is that this test is non-specific as to determine where or what is causing the inflammation. There are several things that will help reduce CRP levels that will be discussed upcomong.
There are certain foods that increase inflammation as well as foods that decrease inflammation. Please note the drawing below in regard to this.
A.A. ——> pge1 fish oil
processed foods
red meat pge2<——-
peanuts
dairy ——> pge3 vegetables
Certain supplements have been shown to be effective in lowering CRP levels. Fiber, 30-50 grams per day of both soluble and insoluble fiber along with Bolouke, enzymes, fish oil and 800 IU of vitamin E daily have been shown to lower CRP levels in humans.
Third Step
Improve Diet
Foods that May Increase Cholesterol Levels
Eating animal foods containing saturated fat is linked to high cholesterol levels and heart disease. A significant amount of saturated fat can be found in conventional beef, pork, veal, poultry with the skins on, cheese, excessive butter, ice cream, and many dairy products that are not low fat.
Palm oil has been shown to elevate cholesterol levels in some studies while some point to a cholesterol lowering effect and with coconut oil there is mixed studies, but recent research is indicating that the structure of coconut oil may be beneficial in many health conditions. Sugar, fructose and processed foods contribute the increase in cholesterol and triglyceride levels. Fructose increases triglyceride levels as this has been shown to be the case in several well conducted studies
Foods to Lower Cholesterol Levels
The role that diet plays in the management of cholesterol can become confusing. Many studies have shown that the increase in cholesterol levels is due to an increased consumption of saturated fat, not necessarily dietary cholesterol. Remember, your body has a built in feed-back mechanism that regulates the amount of cholesterol that is produced in the liver.
Foods that have been shown to lower cholesterol in many double blind and controlled research include fermented milk products, garlic, shitake mushrooms, ginger root, raw nuts, orange juice, dietary fiber, fresh fruit and vegetables. Much of the research is based on the fiber content content as well as these foods supplying plant sterols.
Fourth Step
Miscellaneous Nutrients and Strategies To Help Determine The Cause of High Cholesterol Levels and to Help Lower Cholesterol
1. Do Not Smoke
More and more research is proving that smoke damages the cardiovascular system and also
that it is never too late to quit. Remember, the body is an amazing machine. Given the
correct tools the body can heal itself from most conditions.
2. Reduce Stress
Numerous studies have shown that stress causes many health problems. In relation to
stress, we know that the body responds in many ways including producing excessive cortisol.
Cortisol is a hormone that is secreted from the adrenal cortex when we are under stress. The
problem is elevated cortisol under prolonged states causes a cascade of health problems,
especially heart disease by causing increased inflammation and improper blood sugar
regulation.
3. Increase Fiber
Most Americans do not consume enough fiber. The recommended amount of fiber (soluble
and insoluble) for OPTIMAL intake is considered between 30 and 50 grams. The
unfortunate news is that the average amount of fiber consumed by Americans is only 8
GRAMS PER DAY. Not only does fiber assist in lowering cholesterol but has clinically shown
to lower CRP levels. The relation of chronic inflammation and a increased cardiovascular risk
has been well established.
4. Liver Detoxification
The liver is responsible for hundreds of actions in the body. Our entire body is dependent on
the proper functioning of our liver. Hormones are processed and toxins are dismissed in a
proper liver function. Some nutrients include Milk Thistle, Artichoke, Dandelion, Turmeric,
Guggle, Choline (phosphatidylecholine) inosital, etc. The incorporation of foods that improve
liver function along with decreasing foods know to slow or impede liver function is also
recommended.
5. Regular Exercise
Regular exercise is one of the best ways to increase the HDL or good
cholesterol. Regular exercise also increases insulin sensitivity causing insulin be be more
effective in the body. Look what the new guidelines on the food pyramid are recommending.
60-90 minutes of exercise everyday. The health benefits of regular exercise are too
numerous to cover at this time.
6. Hypothyroidism
Hypothyroidism or low thyroid function has been clinically linked to cardiovascular disease as
well as increased cholesterol and triglycerides. In one large study of 4000 participants,
researchers found that about 2/3 of those diagnosed with hypothyroidism had cholesterol 4
times higher than normal. These individuals had a decrease in thyroxine concentrations
which are the iodine containing hormones secreted from the thyroid gland which main
function is increase cell metabolism.
Several other tips that may give us a clue as to if thyroid is playing a role include the
following:
A. Weight gain around hips. B. Menstrual irregularities. C. Unresponsive thyroid treatment.
Research suggests that hypothyroidism may slow down or decrease the metabolic break
down of fats such as cholesterol. In addition, a dysfunctional thyroid may impair kidney
function and interfere with the activity of the gene (methylenetetrahyrofolate reductase) that
the body depends on to process homocysteine.
7. Hyperthyroidism
Hyperthyroidism is an over-active thyroid gland and has also been linked clinically to
increased risk of cardiovascular disease. Remember the body wants balance. The following
home test is used by many health professionals to determine proper thyroid function.
8. Adrenal Cortical Dysfunction
Consider testing cortisol levels especially if triglycerides are also elevated. Cortisol can
increase the release of catecholamines increasing the release of fatty acids into the blood
stream.
9. Check Blood Levels for Iron
Too much iron in the system can lead to oxidation of fats, cholesterol is a fat.
Hemochromatosis is the number one inherited genetic disease in America today. A simple
blood test from your doctor can determine if you have this condition or not.
10. Fasting Insulin Levels
There is sufficient research showing that elevated insulin levels contributes to metabolic
dysfunction leading to elevations in the lipids. Controlling blood sugar levels is one of the
healthiest things humans can do. Recent research has suggested that diabetes will become
the number one killer of Americans surpassing cancer and heart disease by the year 2010.
Nutrients that have been clinically proven to lower cholesterol and or triglyceride levels
See Additional Literature on Products Listed Below
Styrinol, Phytosterols
Pantethine, Guggle
Red Yeast Rice, CoQ10
Additional Information: at Tailor Made Nutrition or www.tailormadenutrition.com
or
Mark Norman
email mknorman2003@yahoo.com